LC DAD With Optional ESI/MS : An Emerging Gold Standard For Hemp Compliance

Source: US National Institute of Justice (video statements)

This webinar discusses the essential aspects of best practice using liquid chromatography diode array detector (LC-DAD) with optional electrospray ionization mass spectrometry (ESI/MS) for compliance testing of hemp and hemp-derived products. The key topics of this webinar will include: 1) an overview of the most effective LC separation published so far; 2) a description of a simple methanol extraction procedure, consisting of homogenization, ultrasonication/pulverization, centrifugation, filtration, and dilution, to recover cannabinoids from a wide range of samples; 3) how to utilize ultraviolet (UV) detection at multiple wavelengths for optimal sensitivity and improved selectivity; and 4) how to confirm identity of cannabinoids by optional ESI/MS using either high or low-resolution mass spectrometry.

This webinar was hosted by the NIJ Forensic Technology Center of Excellence on June 13, 2024.

(Opinions or points of view expressed represent the speaker and do not necessarily represent the official position or policies of the U.S. Department of Justice. Any product or manufacturer discussed is presented for informational purposes only and do not constitute product approval or endorsement by the U.S. Department of Justice.)

https://www.youtube.com/watch?v=srvW6aGKIoM